Brain lateralization (aka left-brain vs right-brain) is probably not a factor here, it's seldom actually a factor in anything (regardless of what many people think). If it was, I'd be spinning withershins. There is a preference for direction of rotation and diagonal, but that's just a personal thing with some bias for handedness. But it's not really a good reason for doing this in my opinion, because a good mapper shouldn't be mapping in a way that shows a preference. Ideally, it would be nice if this was checked somewhere in the moderation process, but it isn't really so important. Just know mappers, that there is at least one person that gets a kick out of seeing a map where the approaches to spinners have been made in opposite directions. And given my predilection for that sort of thing, I can't really support mirroring because of it... because it would be pointless in a world where all maps are neutral to the effect.
I'm certainly not buying it on the ideal of "useability". The left handed people I know have long since learned how to use a pair of right handed scissors with their left hand (whereas my cross dominance leads me to try using them left handed and failing because I can only use them mirrored from how I use them in my right). Some have even pointed out their dislike for using left handed ones (or even a mouse on the left side)... they've simply adapted to doing it offhand to the point that they gained cross dominance with the tool. In any case, the factor is too minor here to interfere with usability... it's an easy skill to learn to be effectively neutral (if not totally), unless you're being forced to play offhand (I did this for a while).
I'm certainly not buying it on the ideal of "useability". The left handed people I know have long since learned how to use a pair of right handed scissors with their left hand (whereas my cross dominance leads me to try using them left handed and failing because I can only use them mirrored from how I use them in my right). Some have even pointed out their dislike for using left handed ones (or even a mouse on the left side)... they've simply adapted to doing it offhand to the point that they gained cross dominance with the tool. In any case, the factor is too minor here to interfere with usability... it's an easy skill to learn to be effectively neutral (if not totally), unless you're being forced to play offhand (I did this for a while).