As long as you have drivers, wine, and a clean win32 prefix with only dotnet20 on it, I don't really see why it wouldn't work. Is there any way you could update your OS though? Perhaps Wine is too old in 10.04's repositories.
Kurokami wrote:I recently want to run osu! under Ubuntu 10.04, but it is just not starting. I dunno what is the problem, but I really want to play osu! under ubuntu. :3
12.04.2 is the current LTS version.