I've been playing games like these for a long time, and never run into any issues except for in this game. I notice my wrists tend to start hurting mid-map, also affecting my ability to hit keys fast. Other than regular arm exercises, I'm not really sure what to do. Also, my key bindings are very far apart on the keyboard, and that is most comfortable to me as of what I've tried. If anyone has any tips, that would be greatly appreciated.