I'm right handed, but I use my mouse with my left hand (like all my family). I think this suggestion is not really useful, because if we are right handed or left handed with a mouse, there is not really changes ('scuse me for my bad english ><). I play with a friend who is right handed, and I can win with a little practice with the song. If you want to do that, you can, but it won't be useful, I think ^^