TL;DR : no (unless you're a cyborg).
ok since every one is too lazy to explain in detail and I am bored atm, I am gonna do it .
before I start , at the time that I am writing this , to be ranked #50,000 you should have around ~3.285pp,
now to put it simple , the overall pp score is calculated in a way that makes your highest pp score worth it's whole value and the other plays worth slightly less that the plays above them; and thus if you want to get ranked at least #50,000 with one play you need that play to be worth at least ~3.285pp which is the equivalent of doing something like "Spawn of Possession -Apparition (
https://osu.ppy.sh/b/690982) HD DT HR" with a 85% acc .
obviously a normal human can never reach that lever , it's just way beyond human limits (unless you're a hacker or an advanced human from the year 6900).
for more information about the pp system here's a useful link that explains it in details
https://osu.ppy.sh/help/wiki/Performance_PointsI hope that I was useful with thing long (and probably full of english errors xD ) post , GL HF.