I run full ad reds since I find 2 mpen quite useless while having 2 bonus ad is useful at creeping, most of the time you're gonna lasthit'n'run trying to save your q just in case during early levels mid. It also increases spellvamp by a tiny bit lol.
Don't like the hp quints on her either, flat ap allows me to get mres, which gives a lot more survivability, or ap/lvl glyphs while still retaining both passives.
I believe my runepage is better. Minor damage reduction compared to max possible while increased damage trading survivability. And no need to invest over 21 points in 1st mastery tree too.
And also, technically speaking, you don't really need the bonus damage passive much, it's still good if you can get it by lvl 5 or 6 and actually ok if you don't have it until buying ap items. That is, if your rune page is tuned towards survivability.