Basically, there's a in-depth, up-to-date guide over here
TinC wrote:Hey, have mint kde x64, but osu client from playonlinux app run only in x32. How can I fix this and run x64 version? Teach me, senpai.
There are sections on creating 32-Bit Wine prefixes for various conditions such as either using pre-existing or self-compiled wine versions
If you want to get it working as easily as possible I guess taking the PlayOnLinux route is your best bet but you're given various options (papa bless Franc[e]sco for all of his efforts of making and updating his guide)